Program The 4th International Symposium on Process Chemistry 2019 Summer Symposium of The Japanese Society for Process Chemistry



(Main Hall is used unless otherwise stated.)

◆July 24th (Wed)

16:30-17:00  Registration
17:00-19:00  Welcome Reception (Banquet Hall Swan)

◆July 25th (Thu)

8:30 Registration
9:00-9:10  Opening Remarks
Takahiko Akiyama
(Chairperson of ISPC 2019, Gakushuin University, Japan)
9:10-9:50  K-1 (Keynote Lecture)
Nickel-Catalyzed Stereospecific Cross-Coupling and Cross-Electrophile Coupling Reactions
Elizabeth Jarvo (University of California, Irvine, USA)
Chair 1: Osamu Onomura (Nagasaki University, Japan)
9:50-10:30  K-2 (Keynote Lecture)
Innovations in Synthetic Chemistry at MSD: Striving for the Ideal Commercial Manufacturing Process
Kevin Campos (Merck, USA)
Chair 2: Toshiaki Mase (Institute of Molecular Science, Japan)
10:30-10:45  Break

10:45-11:25  K-3 (Keynote Lecture)
Oncology Drug Discovery Efforts in the Japanese Pharmaceutical Company (Eisai Co., Ltd.) and My Next Challenge
Kentaro Yoshimatsu (The Pharmaceutical Society of Japan, Japan)
Chair 3: Yasuhiro Shimada (FUJIFILM Wako Chemical)
11:25-12:05  K-4 (Keynote Lecture)
Simplifying Chemistry through Targeted Route Design: Snippets of Early Stage Process Innovation for Newly Approved Anti-cancer Drugs
Srinivas Oruganti (Dr. Reddy's Institute of Life Sciences, India)
Chair 4: Katsuya Tagami (Eisai, Japan)
12:05-13:10  Lunch (Banquet Hall Sakura)

13:10-13:25  General Assembly of JSPC (in Japanese)

13:25-14:40  Oral Presentation (10 min each)
(1P-12, 1P-16, 1P-20, 1P-27, 1P-29, 1P-51, 1P-75)
Chair 5: Nobuyuki Mase (Shizuoka University, Japan)
14:40-15:50  Poster Presentation (1P-01-1p-xx) (Annex Hall)
Chair 6: Takafumi Ohara(Shionogi, Japan)
15:55-16:35  K-5 (Keynote Lecture)
Process Chemistry as the Ultimate Application of Organic Chemistry
Kai Rossen (Lundbeck in Copenhagen, Denmark)
Chair 7: Shuji Akai (Osaka University, Japan)
16:35-17:15  K-6 (Keynote Lecture)
Contribution from Pharmaceutical Process Chemistry to Green Chemistry and Molecular Diversity
Hideya Mizufune (Spera Pharma, Inc., Japan)
Chair 8: Toshihiko Onoda (Daiichi-Sankyo, Japan)
17:15-18:05  PL-1 (Plenary Lecture)
Development and Applications of Selective Olefin Metathesis Catalysts
Robert Grubbs (California Institute of Technology, USA)
Chair 9: Hironao Sajiki (Gifu Pharmaceutical University, Japan)
18:10-20:40  Banquet (Banquet Hall Sakura)
Welcome Address: Hironao Sajiki
(President of JSPC: Gifu Pharmaceutical University, Japan)
Chair 10: Masahiro Ohshima (Tanabe Mitsubishi, Japan)

◆July 26th (Fri)

9:00-9:40  K-7 (Keynote Lecture)
Peptide and Oligonucleotide Synthesis in Large Scale Using a Novel Solution Phase Approach AJIPHASE ®
Daisuke Takahashi (Ajinomoto Co., Inc., Japan)
Chair 11: Noriaki Murase (Taisho, Japan)
9:40-10:20  K-8 (Keynote Lecture)
Mighty Machines: Rapid and robust scaling of drug substance processes in purpose-built reactors enabled by continuous manufacturing technology
Matthew Bio (Snapdragon Chemistry, Inc., USA)
Chair 12: Mikio Sasaki (Dainippon Sumitomo, Japan)
10:20-10:35  Break

10:35-11:15  K-9 (Keynote Lecture)
Synthetic Route Development for Manufacture of Venetoclax under Expedited Timeline
Yi-yin Ku (Abbvie Inc., USA)
Chair 13: Kaori Ando (Gifu University, Japan)
11:15-11:55  K-10 (Keynote Lecture)
Development of New Molecular Entities: Phase 1
Vikas Shirsath (Jubilant Chemsys Ltd., India)
Chair 14: Shigeru Ieda (Astellas Pharma, Japan)
11:55-13:05  Lunch (Banquet Hall Sakura)

13:05-14:20  Oral Presentation (10 min each)
(2P-10, 2P-15, 2P-20, 2P-21, 2P-27, 2P-50, 2P-65)
Chair 15: Takaaki Sato (Keio University, Japan)
14:20-15:30  Poster Presentation (2P-01-2P-xx) (Annex Hall)
Chair 16: Yoshifumi Hachisu (Daiichi Sankyo, Japan)
15:35-16:15  K-11 (Keynote Lecture)
Review of Continuous Process in SK Biotek
Ryan Seongho Oh (Sk Biotek Co., Ltd., Korea)
Chair 17: Masahiro Ohshima (Mitsubishi Tanabe, Japan)
16:15-17:05  PL-2 (Plenary Lecture)
Toward Continuous Production of Fine Chemicals Using Flow Fine Synthesis
Shu Kobayashi (The University of Tokyo, Japan)
Chair 18: Takayuki Shioiri (Nagoya City University, Japan)
17:05-17:10  Release of JSPC Awardee for Excellence 2019

17:10-17:15  Closing Remarks
Kiyoshi Tomioka (Kyoto University, Japan)


·Please confirm Poster Program.